Bispecifics Abs: New Therapeutic on the Block

New this month, from Chamow & Associates’ Jennifer Bratt, Angela Linderholm, Bryan Monroe and Steven Chamow, is a review on bispecific antibodies (bsAbs) published in BioProcess International titled “Therapeutic IgG-like Bispecific Antibodies and Their Manufacturing Challenges, Part 1”. The authors assemble a detailed overview of a new class of therapeutics in the early stages of development that builds on the technology of monoclonal antibodies.

This in-depth review highlights the modular versatility of bsAbs, compares IgG-like bsAbs to monoclonal antibodies and outlines manufacturing processes such as design considerations, appropriate cell lines for production and downstream processing.

Click to read the article  “Therapeutic IgG-like Bispecific Antibodies and Their Manufacturing Challenges, Part 1”. 

Steven M. Chamow, Ph.D., Principal Consultant |
San Mateo, CA
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