Engineering Micelles for Antibody Capture

Capture of antibodies in biopharmaceutical processes is most commonly performed using affinity chromatography on Protein A.  While Protein A works well, the commercially available chromatography resin is expensive and its…

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Boosting Protein Yield in CHO Culture

Cell growth and product expression are key operating parameters in the manufacture of biologics from CHO cells.  Chemical additives such as sodium butyrate have been used to enhance product expression. …

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How Good are Assays for Host Cell Impurities?

Bioprocesses used to produce recombinant proteins are based on the growth and expansion of living cells in bioreactors. Using the tools of genetic engineering, scientists modify living cells, usually Chinese…

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The Process of CMO Selection for Antibody Development

Companies developing monoclonal antibodies face major challenges in developing and implementing a suitable manufacturing strategy and securing adequate capacity. Planning for products that are under development, and possibly years away…

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