New this month, from Chamow & Associates’ Jennifer Bratt, Angela Linderholm, Bryan Monroe and Steven Chamow, is a review on bispecific antibodies (bsAbs) published in BioProcess International titled “Therapeutic IgG-like Bispecific Antibodies and Their Manufacturing Challenges, Part 1”. The authors assemble a detailed overview of a new class of therapeutics in the early stages of development that builds on the technology of monoclonal antibodies.
This in-depth review highlights the modular versatility of bsAbs, compares IgG-like bsAbs to monoclonal antibodies and outlines manufacturing processes such as design considerations, appropriate cell lines for production and downstream processing.